{"id":1171,"date":"2021-02-09T12:42:04","date_gmt":"2021-02-09T12:42:04","guid":{"rendered":"https:\/\/dfsg.org.uk\/dev\/?page_id=1171"},"modified":"2026-03-06T07:51:30","modified_gmt":"2026-03-06T07:51:30","slug":"research","status":"publish","type":"page","link":"https:\/\/dfsg.org.uk\/dev\/research\/","title":{"rendered":"Research"},"content":{"rendered":"\t\t
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The latest in research...<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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The DFSG keeps up-to-date with recent research to gather the latest information and share updates with families. We also work closely with scientists, clinicians, and research teams, contributing lived experience as a patient expert to support new studies and developments.<\/strong><\/h4>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Givinostat update<\/h3>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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01.12.2025<\/strong><\/p>\n

There has been a recent update on givinostat, a potential treatment for Duchenne muscular dystrophy, which is currently being assessed for use on the NHS in England.<\/p>\n

Givinostat has shown promising results in clinical trials, where it has helped slow the progression of Duchenne. This could make a meaningful difference for children and families living with the condition.<\/p>\n

At the moment, givinostat is being reviewed by the National Institute for Health and Care Excellence (NICE), the body responsible for deciding which treatments should be available through the NHS in England. Following their first meeting on 10 July 2025, the committee has asked for more evidence before making a final decision.<\/p>\n

While it is common for NICE to either recommend a treatment or request further discussion at this stage, in this case, they have asked for additional evidence before deciding. This means a final decision has not yet been made.\u00a0Although this may feel frustrating for families waiting for progress, gathering robust evidence is an important part of ensuring treatments are safe, effective, and accessible in the long term.<\/span><\/p>\n

For the latest updates on givinostat and other research developments, we recommend visiting the\u00a0<\/span>Muscular Dystrophy UK <\/strong>news page, where information is regularly updated.<\/span>
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\n\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tVisit Muscular Dystrophy UK<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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The DMD Hub<\/h3>\t\t\t\t<\/div>\n\t\t\t\t
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The DMD Hub<\/strong> was launched in 2016 as a collaboration between Duchenne UK and two centres of neuromuscular excellence: the John Walton Muscular Dystrophy Research Centre in Newcastle and Great Ormond Street Hospital in London. It brings together a network of specialist sites with trained staff who can deliver clinical trials for Duchenne muscular dystrophy.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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The aim of the DMD Hub is to ensure that everyone living with Duchenne has access to clinical research opportunities, wherever possible.<\/p>\n

The Clinical Trial Finder<\/strong> <\/a>on the DMD Hub website provides clear, up-to-date information on current and upcoming trials across the UK. It includes helpful summaries of each trial so families can understand what\u2019s involved and make informed choices. The Hub also offers guidance on what to consider before taking part in research.<\/p>\n

For updates on the latest clinical trials, medical research and developments in the Duchenne community, you can visit the DMD Hub news section<\/strong><\/a> or sign up to receive the DMD Hub newsletter<\/strong>.<\/a><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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Latest headlines<\/h2>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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First UK patient enrolled in DMD gene therapy trial <\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Important milestone as new DMD treatment is approved in Scotland<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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New research shows increased dystrophin levels in Duchenne<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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Research organisations<\/strong><\/h2>\n
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    Muscular Dystrophy UK<\/p>\n<\/li>\n

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    Duchenne Now<\/p>\n<\/li>\n

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    Action Duchenne<\/p>\n<\/li>\n

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    DMD Registry<\/p>\n<\/li>\n

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    TREAT-NMD<\/p>\n<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t

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    The latest in research… \u00a0 The DFSG keeps up-to-date with recent research to gather the latest information and share updates with families. We also work closely with scientists, clinicians, and research teams, contributing lived experience as a patient expert to support new studies and developments. Givinostat update 01.12.2025 There has been a recent update on […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ngg_post_thumbnail":0,"footnotes":""},"class_list":["post-1171","page","type-page","status-publish","hentry"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/pages\/1171","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/comments?post=1171"}],"version-history":[{"count":32,"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/pages\/1171\/revisions"}],"predecessor-version":[{"id":3660,"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/pages\/1171\/revisions\/3660"}],"wp:attachment":[{"href":"https:\/\/dfsg.org.uk\/dev\/wp-json\/wp\/v2\/media?parent=1171"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}